Research & education
Understand your heart.
Understand your options.
Clear, patient-first cardiovascular education connected to PICC clinicians, clinical programs, and authoritative medical references.
Patient education library
Questions patients are already asking.
Every guide identifies a PICC clinical pathway and is written to educate—not diagnose an individual reader.
Microvascular Disease
INOCA describes ischemic symptoms or evidence of reduced heart blood flow without a major obstructive coronary blockage.
Read guide →What is microvascular angina?Microvascular angina involves dysfunction in the heart’s smallest blood vessels and may require evaluation beyond a standard angiogram.
Read guide →Why do I have chest pain if my angiogram was normal?A non-obstructive angiogram does not rule out every cardiac cause of chest pain, including microvascular and vasomotor conditions.
Read guide →What is coronary vasospasm?Coronary vasospasm is temporary tightening of a coronary artery that can reduce blood flow and produce symptoms.
Read guide →Physiology
Coronary flow reserve compares blood flow under resting and increased-demand conditions to help assess coronary circulation.
Read guide →What is FFR?Fractional flow reserve is an invasive physiologic measurement used to assess whether a coronary narrowing limits blood flow.
Read guide →What is iFR?Instantaneous wave-free ratio is another invasive pressure-based method used to evaluate the functional importance of a coronary narrowing.
Read guide →What is angiography-based FFR?Angiography-based physiology estimates the functional importance of a narrowing from coronary angiographic images.
Read guide →What is FFRangio?FFRangio is one form of angiography-derived coronary physiology that estimates pressure effects from routine angiographic images without replacing the clinician’s full assessment.
Read guide →Coronary Disease
The decision depends on symptoms, anatomy, physiology, overall risk, and how the findings fit the full clinical picture.
Read guide →What is complex PCI?Complex PCI refers to coronary intervention involving challenging anatomy, patient risk, or procedural planning needs.
Read guide →What is high-risk PCI?High-risk PCI involves careful planning for selected patients whose clinical status or coronary anatomy increases procedural complexity.
Read guide →What is a chronic total occlusion?A chronic total occlusion is a coronary artery that has been completely blocked for an extended period.
Read guide →How are heavily calcified coronary arteries treated?Treatment planning may use specialized imaging and plaque-modification techniques when intervention is appropriate.
Read guide →Intracoronary Imaging
Intravascular ultrasound uses a miniature ultrasound device inside the artery to show the vessel and plaque in cross-section.
Read guide →What is OCT?Optical coherence tomography uses light-based imaging inside a coronary artery to provide detailed information for selected procedures.
Read guide →IVUS versus OCT: how are they different?IVUS uses ultrasound and OCT uses near-infrared light; each can answer different questions about vessel size, plaque, and a coronary procedure result.
Read guide →Cardiac Imaging
CCTA is a noninvasive CT examination that shows the coronary arteries and plaque.
Read guide →CCTA versus stress testingCCTA evaluates coronary anatomy, while stress testing assesses the heart’s response to increased demand; the appropriate test depends on the question.
Read guide →What is FFRCT?FFRCT uses coronary CT data and computational analysis to estimate the physiologic effect of coronary narrowings.
Read guide →What is AI coronary plaque analysis?AI-enabled analysis can help quantify and characterize plaque seen on coronary CT when the information is clinically useful.
Read guide →Prevention
A coronary calcium score measures calcified plaque and can add information to a clinician-guided risk assessment.
Read guide →Why is cardiovascular risk higher among South Asians?South Asian patients may face earlier or underestimated cardiometabolic risk, making culturally informed prevention important.
Read guide →Blood Pressure
Resistant hypertension generally describes blood pressure that remains above goal despite an appropriate multi-medication strategy and requires structured evaluation.
Read guide →What is renal denervation?Renal denervation is a catheter-based procedure considered for selected patients with hypertension after clinical evaluation.
Read guide →Cholesterol
Lipoprotein(a) is an inherited lipid particle associated with cardiovascular risk and is measured with a blood test.
Read guide →What is familial hypercholesterolemia?Familial hypercholesterolemia is an inherited condition associated with very high LDL cholesterol and early cardiovascular risk.
Read guide →What happens if I cannot tolerate a statin?A clinician can review symptoms, prior treatments, cardiovascular risk, and evidence-based alternatives rather than abandoning lipid care.
Read guide →What are PCSK9 therapies?PCSK9-targeting treatments are prescription options that can substantially lower LDL cholesterol for appropriately selected patients after an individualized risk and treatment review.
Read guide →What is inclisiran?Inclisiran is a prescription small-interfering RNA therapy that lowers LDL cholesterol by reducing production of PCSK9 and is considered within a clinician-directed lipid plan.
Read guide →Cardiometabolic Health
Aortic Valve
Possible symptoms include reduced exercise tolerance, shortness of breath, chest pressure, or fainting, but individual assessment is essential.
Read guide →When is TAVR considered?TAVR may be considered for severe aortic stenosis after evaluation of symptoms, imaging, overall health, anatomy, and treatment options.
Read guide →Vascular Health
Second Opinions
12-month editorial plan
A focused path to long-term cardiovascular authority.
Each month answers a cluster of real patient questions, connects to a PICC program, and follows the same medical-review standard.
- Month 1INOCA, microvascular angina, and chest pain with a normal angiogram
- Month 2FFR, iFR, and angiography-derived coronary physiology
- Month 3IVUS, OCT, and physiology-guided PCI
- Month 4Complex PCI, CTO, and calcified coronary disease
- Month 5CCTA, calcium scoring, and FFRCT
- Month 6AI coronary plaque analysis and early detection
- Month 7Resistant hypertension and renal denervation
- Month 8Lipoprotein(a), familial cholesterol, and treatment intolerance
- Month 9Diabetes, obesity, and cardiometabolic cardiovascular risk
- Month 10Aortic stenosis symptoms and TAVR evaluation
- Month 11Peripheral artery disease and vascular symptoms
- Month 12South Asian risk and cardiovascular second opinions
PICC podcast
Cardio Conversations with Jen and Ankit
Eight concise conversations connecting modern cardiovascular science with questions patients and clinicians ask in everyday care.
Listen or watch on iHeart ↗Seeing the Invisible: AI and CT-FFR
AI in Cardiology: The Future is Now
The Cath Lab Decision
Cholesterol: More Than Just a Number
The Mystery of Microvascular Angina
Plaque Detectives: How We Spot Trouble Early
Heart Disease 101
Patient education
Clear background information for informed conversations with your care team.
Last updated
August 22, 2026
Education does not replace diagnosis or personal medical advice.