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Advanced cardiovascular technology

Technology should answer a clinical question.

PICC brings advanced imaging, coronary physiology, intracoronary imaging, and selected interventional options into the larger story of symptoms, risk, and long-term care—not simply because the technology exists.

Color-coded coronary CT plaque analysis with vessel measurements and plaque summary.
01

Can noninvasive imaging show plaque, anatomy, and whether a narrowing may matter?

CT plaque and advanced coronary CT

CCTA, AI-enabled plaque analysis, calcium scoring, and FFRCT may add anatomic and physiologic information when clinically appropriate.

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Coronary angiography-based FFR analysis with vessel model and diameter graph.
02

Is a coronary narrowing meaningfully restricting blood flow?

FFR and coronary physiology

FFR, iFR, and angiography-based physiology place a narrowing in functional context and can support either treatment or medical care.

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Cross-sectional intravascular ultrasound view of a coronary artery.
03

What does the inside of the coronary artery look like?

IVUS intracoronary imaging

Intravascular ultrasound images the artery from within and can help assess plaque, size the vessel, and optimize selected procedures.

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Coronary physiology assessment screen showing pressure curves and microvascular measurements.
04

Could microvascular or vasomotor function explain symptoms when major arteries appear open?

Microvascular assessment

Coronary function testing and physiology curves, including CFR and IMR, may help evaluate persistent symptoms when appropriate.

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Fluoroscopic image of catheter-based circulatory support during a cardiac procedure.
05

Would carefully selected support help during a high-risk coronary procedure?

Impella, ECP, and selected circulatory support

Mechanical circulatory support may be considered for selected high-risk procedures after individualized clinical assessment.

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Fluoroscopic image of a renal artery catheter used during renal denervation.
06

Could a procedure be considered for selected difficult-to-control hypertension?

Renal denervation

Renal denervation is evaluated only after confirming the blood-pressure pattern and reviewing medications and secondary causes.

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Patient questions

Understanding how technology fits into care.

These answers are general education. Your clinician should explain why a particular test or procedure is—or is not—appropriate for you.

Does every patient need advanced testing?

No. A test is considered when it can answer a specific clinical question, clarify risk, or change a treatment decision.

Does more technology mean I will need a procedure?

No. Advanced imaging or physiology may support prevention, medical therapy, observation, another test, or intervention depending on the full clinical picture.

What is the difference between anatomy and physiology?

Anatomy shows the structure of an artery and plaque. Physiology evaluates whether a narrowing meaningfully limits blood flow.

What is the difference between IVUS and OCT?

Both look from inside a coronary artery. IVUS uses ultrasound, while OCT uses near-infrared light and provides very high-resolution detail. The clinical question guides the choice.

Can coronary CT replace cardiac catheterization?

Sometimes CCTA answers the question noninvasively; other situations require invasive measurements or treatment. A clinician selects the appropriate pathway.

Where can I learn more about a specific technology?

Each item below links to the corresponding PICC clinical program, and the Education Hub contains additional medically reviewed patient guides.

The PICC principle

More information should create a clearer decision—not automatically more procedures.

Some findings support intervention. Others support prevention, medical therapy, additional observation, or reassurance. The right tool is the one that helps the patient and clinician choose the next right step.

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Medically reviewed by
Ankitkumar Patel, MD, MPH, FACC, FSCAI, RPVI

Last reviewed
August 22, 2026

Educational information only. It does not replace personal medical advice.